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PIAS3 activates the intrinsic apoptotic pathway in non-small cell lung cancer cells independent of p53 status
Protein inhibitor of activated STAT3 (PIAS3) is an endogenous inhibitor of STAT3 that negatively regulates STAT3 transcriptional activity and cell growth and demonstrates limited expression in the majority of human squamous cell carcinomas of the lung. In the present study we sought to determine if...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4199747/ https://ncbi.nlm.nih.gov/pubmed/23959540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28448 |
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