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How Structure Defines Affinity in Protein-Protein Interactions

Protein-protein interactions (PPI) in nature are conveyed by a multitude of binding modes involving various surfaces, secondary structure elements and intermolecular interactions. This diversity results in PPI binding affinities that span more than nine orders of magnitude. Several early studies att...

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Detalhes bibliográficos
Main Authors: Erijman, Ariel, Rosenthal, Eran, Shifman, Julia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199723/
https://ncbi.nlm.nih.gov/pubmed/25329579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110085
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