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The impact of age on oncogenic potential: tumor-initiating cells and the brain microenvironment

Paradoxically, aging leads to both decreased regenerative capacity in the brain and an increased risk of tumorigenesis, particularly the most common adult-onset brain tumor, glioma. A shared factor contributing to both phenomena is thought to be agerelated alterations in neural progenitor cells (NPC...

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Detalhes bibliográficos
Main Authors: Stoll, Elizabeth A., Horner, Philip J., Rostomily, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199664/
https://ncbi.nlm.nih.gov/pubmed/23711239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12104
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