Clinical problems of colorectal cancer and endometrial cancer cases with unknown cause of tumor mismatch repair deficiency (suspected Lynch syndrome)

Carriers of a germline mutation in one of the DNA mismatch repair (MMR) genes have a high risk of developing numerous different cancers, predominantly colorectal cancer and endometrial cancer (known as Lynch syndrome). MMR gene mutation carriers develop tumors with MMR deficiency identified by tumor...

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Bibliographische Detailangaben
Hauptverfasser: Buchanan, Daniel D, Rosty, Christophe, Clendenning, Mark, Spurdle, Amanda B, Win, Aung Ko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2014
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199650/
https://ncbi.nlm.nih.gov/pubmed/25328415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S48625
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