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Synthesis and biological investigations of a ZnPc-antiCEA bioconjugate for imaging of colorectal cancer
Two zinc(II) phthalocyanines (ZnPcs) were conjugated with a monoclonal antibody (MAb) directed against carcinoembryonic antigen (CEA), using an in situ activated carboxylic acid on the ZnPcs. The bioconjugate with the highest ZnPc/MAb ratio of 3 was investigated in vitro for its ability to target an...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4199585/ https://ncbi.nlm.nih.gov/pubmed/25328375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S108842461250143X |
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