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ZTF-8 Interacts with the 9-1-1 Complex and Is Required for DNA Damage Response and Double-Strand Break Repair in the C. elegans Germline
Germline mutations in DNA repair genes are linked to tumor progression. Furthermore, failure in either activating a DNA damage checkpoint or repairing programmed meiotic double-strand breaks (DSBs) can impair chromosome segregation. Therefore, understanding the molecular basis for DNA damage respons...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Public Library of Science
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4199516/ https://ncbi.nlm.nih.gov/pubmed/25329393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004723 |
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