Hsp40s Specify Functions of Hsp104 and Hsp90 Protein Chaperone Machines

Hsp100 family chaperones of microorganisms and plants cooperate with the Hsp70/Hsp40/NEF system to resolubilize and reactivate stress-denatured proteins. In yeast this machinery also promotes propagation of prions by fragmenting prion polymers. We previously showed the bacterial Hsp100 machinery coo...

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Bibliographic Details
Main Authors: Reidy, Michael, Sharma, Ruchika, Shastry, Shankar, Roberts, Brittany-Lee, Albino-Flores, Ivan, Wickner, Sue, Masison, Daniel C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199505/
https://ncbi.nlm.nih.gov/pubmed/25329162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004720
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