Evolutionarily diverse determinants of meiotic DNA break and recombination landscapes across the genome

Fission yeast Rec12 (Spo11 homolog) initiates meiotic recombination by forming developmentally programmed DNA double-strand breaks (DSBs). DSB distributions influence patterns of heredity and genome evolution, but the basis of the highly nonrandom choice of Rec12 cleavage sites is poorly understood,...

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Dades bibliogràfiques
Autors principals: Fowler, Kyle R., Sasaki, Mariko, Milman, Neta, Keeney, Scott, Smith, Gerald R.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199369/
https://ncbi.nlm.nih.gov/pubmed/25024163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.172122.114
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