Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells.

Wound repair and tumor vascularization depend upon blood vessel growth into hypoxic tissue. Although hypoxia slows endothelial cell (EC) proliferation and suppresses EC basic fibroblast growth factor (bFGF) expression, we report that macrophages (MPs) exposed to PO2 approximately 12-14 torr (1 torr...

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Bibliographic Details
Main Authors: Kuwabara, K, Ogawa, S, Matsumoto, M, Koga, S, Clauss, M, Pinsky, D J, Lyn, P, Leavy, J, Witte, L, Joseph-Silverstein, J
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC41993/
https://ncbi.nlm.nih.gov/pubmed/7538678
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