Hypoxia-mediated induction of acidic/basic fibroblast growth factor and platelet-derived growth factor in mononuclear phagocytes stimulates growth of hypoxic endothelial cells.

Wound repair and tumor vascularization depend upon blood vessel growth into hypoxic tissue. Although hypoxia slows endothelial cell (EC) proliferation and suppresses EC basic fibroblast growth factor (bFGF) expression, we report that macrophages (MPs) exposed to PO2 approximately 12-14 torr (1 torr...

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Detalhes bibliográficos
Main Authors: Kuwabara, K, Ogawa, S, Matsumoto, M, Koga, S, Clauss, M, Pinsky, D J, Lyn, P, Leavy, J, Witte, L, Joseph-Silverstein, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC41993/
https://ncbi.nlm.nih.gov/pubmed/7538678
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