Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice

DNA damage and telomere dysfunction shorten organismal lifespan. Here we show that oral glucose administration at advanced age increases health and lifespan of telomere dysfunctional mice. The study reveals that energy consumption increases in telomere dysfunctional cells resulting in enhanced gluco...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Missios, Pavlos, Zhou, Yuan, Guachalla, Luis Miguel, von Figura, Guido, Wegner, Andre, Chakkarappan, Sundaram Reddy, Binz, Tina, Gompf, Anne, Hartleben, Götz, Burkhalter, Martin D., Wulff, Veronika, Günes, Cagatay, Sattler, Rui Wang, Song, Zhangfa, Illig, Thomas, Klaus, Susanne, Böhm, Bernhard O., Wenz, Tina, Hiller, Karsten, Rudolph, K. Lenhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199114/
https://ncbi.nlm.nih.gov/pubmed/25233189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5924
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados