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Telomere dysfunction puts the brakes on oncogene-induced cancers

EMBO J 31 13, 2839–2851 (2012); published online 05082012 Senescence represents a major tumour suppressor checkpoint activated by telomere dysfunction or cellular stress factors such as oncogene activation. In this issue of The EMBO Journal, Suram et al (2012) reveal a surprising interconnection bet...

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Autores principales: Günes, Cagatay, Rudolph, Karl Lenhard
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395100/
https://ncbi.nlm.nih.gov/pubmed/22643218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.162
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