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Lynch Syndrome: An Updated Review

Lynch syndrome is one of the most common cancer susceptibility syndromes. Individuals with Lynch syndrome have a 50%–70% lifetime risk of colorectal cancer, 40%–60% risk of endometrial cancer, and increased risks of several other malignancies. It is caused by germline mutations in the DNA mismatch r...

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Detalhes bibliográficos
Main Authors: Sehgal, Rishabh, Sheahan, Kieran, O’Connell, Patrick R., Hanly, Ann M., Martin, Sean T., Winter, Desmond C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198913/
https://ncbi.nlm.nih.gov/pubmed/24978665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes5030497
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