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5-aza-2′-deoxycytidine-mediated c-myc Down-regulation Triggers Telomere-dependent Senescence by Regulating Human Telomerase Reverse Transcriptase in Chronic Myeloid Leukemia()

Increased proliferation rates as well as resistance to apoptosis are considered major obstacles for the treatment of patients with chronic myelogenous leukemia (CML), thus highlighting the need for novel therapeutic approaches. Since senescence has been recognized as a physiological barrier against...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Grandjenette, Cindy, Schnekenburger, Michael, Karius, Tommy, Ghelfi, Jenny, Gaigneaux, Anthoula, Henry, Estelle, Dicato, Mario, Diederich, Marc
التنسيق: Artigo
اللغة:Inglês
منشور في: Neoplasia Press 2014
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198755/
https://ncbi.nlm.nih.gov/pubmed/24970385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2014.05.009
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