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Regulation of epigenetic traits of the glutathione S-transferase P1 gene: from detoxification toward cancer prevention and diagnosis

Glutathione S-transferases (GSTs) are phase II drug detoxifying enzymes that play an essential role in the maintenance of cell integrity and protection against DNA damage by catalyzing the conjugation of glutathione to a wide variety of exo- and endogenous electrophilic substrates. Glutathione S-tra...

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Detalhes bibliográficos
Main Authors: Schnekenburger, Michael, Karius, Tommy, Diederich, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4100573/
https://ncbi.nlm.nih.gov/pubmed/25076909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00170
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