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4-Methylumbelliferone inhibits ovarian cancer growth by suppressing thymidine phosphorylase expression

BACKGROUND: 4-Methylumbelliferone (4-MU), a hyaluronan (HA) synthesis inhibitor, has antitumor activity in cancer cells. However, few studies have focused on its effects on ovarian cancer. The aim of this study was to investigate the effects of 4-MU on ovarian cancer and to elucidate its mechanism o...

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Detalhes bibliográficos
Main Authors: Tamura, Ryosuke, Yokoyama, Yoshihito, Yoshida, Hidemi, Imaizumi, Tadaatsu, Mizunuma, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198731/
https://ncbi.nlm.nih.gov/pubmed/25304388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-014-0094-2
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