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Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers

BACKGROUND: Aberrant DNA methylation is a hallmark of many cancers. Classically there are two types of endometrial cancer, endometrioid adenocarcinoma (EAC), or Type I, and uterine papillary serous carcinoma (UPSC), or Type II. However, the whole genome DNA methylation changes in these two classical...

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Detalhes bibliográficos
Main Authors: Zhang, Bo, Xing, XiaoYun, Li, Jing, Lowdon, Rebecca F, Zhou, Yan, Lin, Nan, Zhang, Baoxue, Sundaram, Vasavi, Chiappinelli, Katherine B, Hagemann, Ian S, Mutch, David G, Goodfellow, Paul J, Wang, Ting
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198682/
https://ncbi.nlm.nih.gov/pubmed/25286960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-868
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