The Rac1 Inhibitor NSC23766 Suppresses CREB Signaling by Targeting NMDA Receptor Function

NMDA receptor signaling plays a complex role in CREB activation and CREB-mediated gene transcription, depending on the subcellular location of NMDA receptors, as well as how strongly they are activated. However, it is not known whether Rac1, the prototype of Rac GTPase, plays a role in neuronal CREB...

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Autores principales: Hou, Hailong, Chávez, Andrés E., Wang, Chih-Chieh, Yang, Hongtian, Gu, Hua, Siddoway, Benjamin A., Hall, Benjamin J., Castillo, Pablo E., Xia, Houhui
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2014
Materias:
Brief Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198541/
https://ncbi.nlm.nih.gov/pubmed/25319697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1659-14.2014
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