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LRP4 Is Critical for Neuromuscular Junction Maintenance
The neuromuscular junction (NMJ) is a synapse between motor neurons and skeletal muscle fibers, and is critical for control of muscle contraction. Its formation requires neuronal agrin that acts by binding to LRP4 to stimulate MuSK. Mutations have been identified in agrin, MuSK, and LRP4 in patients...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4198535/ https://ncbi.nlm.nih.gov/pubmed/25319686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1733-14.2014 |
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