LRP4 Is Critical for Neuromuscular Junction Maintenance

The neuromuscular junction (NMJ) is a synapse between motor neurons and skeletal muscle fibers, and is critical for control of muscle contraction. Its formation requires neuronal agrin that acts by binding to LRP4 to stimulate MuSK. Mutations have been identified in agrin, MuSK, and LRP4 in patients...

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Bibliografiske detaljer
Main Authors: Barik, Arnab, Lu, Yisheng, Sathyamurthy, Anupama, Bowman, Andrew, Shen, Chengyong, Li, Lei, Xiong, Wen-cheng, Mei, Lin
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198535/
https://ncbi.nlm.nih.gov/pubmed/25319686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1733-14.2014
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