Safety and clinical activity of 5-aza-2’-deoxycytidine (decitabine) with or without Hyper-CVAD in relapsed/refractory acute lymphocytic leukaemia

To test the safety and activity of 5-aza-2’-deoxycytidine (decitabine) in patients with relapsed/refractory acute lymphocytic leukaemia (ALL), we conducted a phase 1 study with two parts: administering decitabine alone or in combination with Hyper-CVAD (fractionated cyclophosphamide, vincristine, do...

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Detalhes bibliográficos
Main Authors: Benton, Christopher B, Thomas, Deborah A, Yang, Hui, Ravandi, Farhad, Rytting, Michael, O’Brien, Susan, Franklin, Anna R, Borthakur, Gautam, Dara, Samuel, Kwari, Monica, Pierce, Sherry R, Jabbour, Elias, Kantarjian, Hagop, Garcia-Manero, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198465/
https://ncbi.nlm.nih.gov/pubmed/25066676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13050
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