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Targeting the MET receptor tyrosine kinase in non-small cell lung cancer: emerging role of tivantinib

MET receptor tyrosine kinase and its natural ligand, hepatocyte growth factor, have been implicated in a variety of cancers, including non-small cell lung cancer (NSCLC). Mechanisms by which cellular deregulation of MET occurs include overexpression, genomic amplification, mutation, or alternative s...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Agwa, Eberechi S, Ma, Patrick C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198276/
https://ncbi.nlm.nih.gov/pubmed/25328417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S37345
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