Mimotope-Based Vaccines of Leishmania infantum Antigens and Their Protective Efficacy against Visceral Leishmaniasis

BACKGROUND: The development of cost-effective prophylactic strategies to prevent leishmaniasis has become a high-priority. The present study has used the phage display technology to identify new immunogens, which were evaluated as vaccines in the murine model of visceral leishmaniasis (VL). Epitope-...

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Autors principals: Costa, Lourena Emanuele, Goulart, Luiz Ricardo, Pereira, Nathália Cristina de Jesus, Lima, Mayara Ingrid Sousa, Duarte, Mariana Costa, Martins, Vivian Tamietti, Lage, Paula Sousa, Menezes-Souza, Daniel, Ribeiro, Tatiana Gomes, Melo, Maria Norma, Fernandes, Ana Paula, Soto, Manuel, Tavares, Carlos Alberto Pereira, Chávez-Fumagalli, Miguel Angel, Coelho, Eduardo Antonio Ferraz
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198211/
https://ncbi.nlm.nih.gov/pubmed/25333662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110014
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