Tissue MicroRNAs as Predictors of Outcome in Patients with Metastatic Colorectal Cancer Treated with First Line Capecitabine and Oxaliplatin with or without Bevacizumab

PURPOSE: We tested the hypothesis that expression of microRNAs (miRNAs) in cancer tissue can predict effectiveness of bevacizumab added to capecitabine and oxaliplatin (CAPEOX) in patients with metastatic colorectal cancer (mCRC). EXPERIMENTAL DESIGN: Patients with mCRC treated with first line CAPEO...

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Hauptverfasser: Boisen, Mogens K., Dehlendorff, Christian, Linnemann, Dorte, Nielsen, Boye S., Larsen, Jim S., Østerlind, Kell, Nielsen, Svend E., Tarpgaard, Line S., Qvortrup, Camilla, Pfeiffer, Per, Holländer, Niels H., Keldsen, Nina, Hansen, Torben F., Jensen, Brita B., Høgdall, Estrid V. S., Jensen, Benny V., Johansen, Julia S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198118/
https://ncbi.nlm.nih.gov/pubmed/25329796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109430
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