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Drosophila Tribbles Antagonizes Insulin Signaling-Mediated Growth and Metabolism via Interactions with Akt Kinase

Drosophila Tribbles (Trbl) is the founding member of the Trib family of kinase-like docking proteins that modulate cell signaling during proliferation, migration and growth. In a wing misexpression screen for Trbl interacting proteins, we identified the Ser/Thr protein kinase Akt1. Given the central...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Das, Rahul, Sebo, Zachary, Pence, Laramie, Dobens, Leonard L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198113/
https://ncbi.nlm.nih.gov/pubmed/25329475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109530
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