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Metaxin, a gene contiguous to both thrombospondin 3 and glucocerebrosidase, is required for embryonic development in the mouse: implications for Gaucher disease.

We have identified a murine gene, metaxin, that spans the 6-kb interval separating the glucocerebrosidase gene (GC) from the thrombospondin 3 gene on chromosome 3E3-F1. Metaxin and GC are transcribed convergently; their major polyadenylylation sites are only 431 bp apart. On the other hand, metaxin...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bornstein, P, McKinney, C E, LaMarca, M E, Winfield, S, Shingu, T, Devarayalu, S, Vos, H L, Ginns, E I
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41981/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7753840/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.10.4547
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