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Meiotic cohesin STAG3 is required for chromosome axis formation and sister chromatid cohesion

The cohesin complex is essential for mitosis and meiosis. The specific meiotic roles of individual cohesin proteins are incompletely understood. We report in vivo functions of the only meiosis-specific STAG component of cohesin, STAG3. Newly generated STAG3-deficient mice of both sexes are sterile w...

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Autors principals: Winters, Tristan, McNicoll, Francois, Jessberger, Rolf
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198028/
https://ncbi.nlm.nih.gov/pubmed/24797474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387330
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