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Meiotic cohesin STAG3 is required for chromosome axis formation and sister chromatid cohesion
The cohesin complex is essential for mitosis and meiosis. The specific meiotic roles of individual cohesin proteins are incompletely understood. We report in vivo functions of the only meiosis-specific STAG component of cohesin, STAG3. Newly generated STAG3-deficient mice of both sexes are sterile w...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BlackWell Publishing Ltd
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4198028/ https://ncbi.nlm.nih.gov/pubmed/24797474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387330 |
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