Molecular Mechanisms Underlying Fasting Modulated Liver Insulin Sensitivity and Metabolism in Male Lipodystrophic Bscl2/Seipin-Deficient Mice

Bscl2(−/−) mice recapitulate many of the major metabolic manifestations in Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2) individuals, including lipodystrophy, hepatomegly, hepatic steatosis, and insulin resistance. The mechanisms that underlie hepatic steatosis and insulin resistance in...

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Hlavní autoři: Chen, Weiqin, Zhou, Hongyi, Saha, Pradip, Li, Luge, Chan, Lawrence
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2014
Témata:
Energy Balance-Obesity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197977/
https://ncbi.nlm.nih.gov/pubmed/25093462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1292
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