Reversal of Diet-Induced Obesity Increases Insulin Transport into Cerebrospinal Fluid and Restores Sensitivity to the Anorexic Action of Central Insulin in Male Rats

Diet-induced obesity (DIO) reduces the ability of centrally administered insulin to reduce feeding behavior and also reduces the transport of insulin from the periphery to the central nervous system (CNS). The current study was designed to determine whether reversal of high-fat DIO restores the anor...

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Detalhes bibliográficos
Main Authors: Begg, Denovan P., Mul, Joram D., Liu, Min, Reedy, Brianne M., D'Alessio, David A., Seeley, Randy J., Woods, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Energy Balance-Obesity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578991/
https://ncbi.nlm.nih.gov/pubmed/23337529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1929
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