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Reversal of Diet-Induced Obesity Increases Insulin Transport into Cerebrospinal Fluid and Restores Sensitivity to the Anorexic Action of Central Insulin in Male Rats

Diet-induced obesity (DIO) reduces the ability of centrally administered insulin to reduce feeding behavior and also reduces the transport of insulin from the periphery to the central nervous system (CNS). The current study was designed to determine whether reversal of high-fat DIO restores the anor...

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Hlavní autoři: Begg, Denovan P., Mul, Joram D., Liu, Min, Reedy, Brianne M., D'Alessio, David A., Seeley, Randy J., Woods, Stephen C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578991/
https://ncbi.nlm.nih.gov/pubmed/23337529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1929
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