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The cell of origin and subtype of K-Ras-induced lung tumors are modified by Notch and Sox2
Cell type-specific conditional activation of oncogenic K-Ras is a powerful tool for investigating the cell of origin of adenocarcinomas in the mouse lung. Our previous studies showed that K-Ras activation with a CC10(Scgb1a1)-CreER driver leads to adenocarcinoma in a subset of alveolar type II cells...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197950/ https://ncbi.nlm.nih.gov/pubmed/25184679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.243717.114 |
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