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A Pipeline for Copy Number Variation Detection based on Principal Component Analysis
DNA copy number variation (CNV), an important structural variation, is known to be pervasive in the human genome and the determination of CNVs is essential to understanding their potential effects on the susceptibility to diseases. However, CNV detection using SNP array data is challenging due to th...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197848/ https://ncbi.nlm.nih.gov/pubmed/22255943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/IEMBS.2011.6091763 |
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