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A Pipeline for Copy Number Variation Detection based on Principal Component Analysis

DNA copy number variation (CNV), an important structural variation, is known to be pervasive in the human genome and the determination of CNVs is essential to understanding their potential effects on the susceptibility to diseases. However, CNV detection using SNP array data is challenging due to th...

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Hlavní autoři: Chen, Jiayu, Liu, Jingyu, Calhoun, Vince D., Boutte, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197848/
https://ncbi.nlm.nih.gov/pubmed/22255943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/IEMBS.2011.6091763
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