Characteristic bimodal profiles of RNA polymerase II at thousands of active mammalian promoters

BACKGROUND: In mammals, ChIP-seq studies of RNA polymerase II (PolII) occupancy have been performed to reveal how recruitment, initiation and pausing of PolII may control transcription rates, but the focus is rarely on obtaining finely resolved profiles that can portray the progression of PolII thro...

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Detalhes bibliográficos
Main Authors: Quinodoz, Mathieu, Gobet, Cédric, Naef, Felix, Gustafson, Kyle B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197824/
https://ncbi.nlm.nih.gov/pubmed/24972996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-6-r85
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