Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells

BACKGROUND: The TET family of dioxygenases catalyze conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), but their involvement in establishing normal 5mC patterns during mammalian development and their contributions to aberrant control of 5mC during cellular transformation remain...

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Hauptverfasser: Putiri, Emily L, Tiedemann, Rochelle L, Thompson, Joyce J, Liu, Chunsheng, Ho, Thai, Choi, Jeong-Hyeon, Robertson, Keith D
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197818/
https://ncbi.nlm.nih.gov/pubmed/24958354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-6-r81
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