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Structure of the Trypanosoma cruzi protein tyrosine phosphatase TcPTP1, a potential therapeutic target for Chagas’ disease

Chagas’ disease, a neglected tropical affliction transmitted by the flagellated protozoan Trypanosoma cruzi, is prevalent in Latin America and affects nearly 18 million people worldwide, yet few approved drugs are available to treat the disease. Moreover, the currently available drugs exhibit severe...

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Bibliographic Details
Main Authors: Lountos, George T., Tropea, Joseph E., Waugh, David S.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197799/
https://ncbi.nlm.nih.gov/pubmed/23137716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2012.10.006
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