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GEMINs: potential therapeutic targets for spinal muscular atrophy?

The motor neuron degenerative disease spinal muscular atrophy (SMA) remains one of the most frequently inherited causes of infant mortality. Afflicted patients loose the survival motor neuron 1 (SMN1) gene but retain one or more copies of SMN2, a homolog that is incorrectly spliced. Primary treatmen...

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Détails bibliographiques
Auteurs principaux: Borg, Rebecca, Cauchi, Ruben J.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197776/
https://ncbi.nlm.nih.gov/pubmed/25360080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00325
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