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Elevated postinjury thrombospondin 1–CD47 triggering aids differentiation of patients' defective inflammatory CD1a(+)dendritic cells

A subset of Pts develops dysfunctional MO to inflammatory DC differentiation and immunosuppression. MDDC, a newly described DC subset, is pivotal in initiating antibacterial responses. Endogenous proteins are known to alter MO to MDDC differentiation. In particular, trauma-elevated TSP-1, a protein...

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Detalhes bibliográficos
Main Authors: Bandyopadhyay, Gautam, Bandyopadhyay, Sanjukta, Bankey, Paul E., Miller-Graziano, Carol L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197567/
https://ncbi.nlm.nih.gov/pubmed/25001859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4MA0214-077R
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