Dissolution Testing of Hardly Soluble Materials by Surface Sensitive Techniques: Clotrimazole from an Insoluble Matrix

PURPOSE: The low aqueous solubility of many drugs impedes detailed investigation as the detection limit of standard testing routines is limited. This is further complicated within application relevant thin films typical used in patches or stripes for buccal or topical routes. METHODS: In this work a...

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Hlavní autoři: Ehmann, Heike M. A., Winter, Sascha, Griesser, Thomas, Keimel, Roman, Schrank, Simone, Zimmer, Andreas, Werzer, Oliver
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197366/
https://ncbi.nlm.nih.gov/pubmed/24752480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1368-5
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