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Surface-Induced Polymorphism as a Tool for Enhanced Dissolution: The Example of Phenytoin

[Image: see text] Polymorphism and morphology can represent key factors tremendously limiting the bioavailability of active pharmaceutical ingredients (API), in particular, due to solubility issues. Within this work, the generation of a yet unknown surface-induced polymorph (SIP) of the model drug,...

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Bibliografische gegevens
Gepubliceerd in:Cryst Growth Des
Hoofdauteurs: Reischl, Daniela, Röthel, Christian, Christian, Paul, Roblegg, Eva, Ehmann, Heike M. A., Salzmann, Ingo, Werzer, Oliver
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2015
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561386/
https://ncbi.nlm.nih.gov/pubmed/26366128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.cgd.5b01002
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