Increased frequency and function of KIR2DL1-3(+) NK cells in primary HIV-1 infection are determined by HLA-C group haplotypes

Acquisition and maintenance of NK cell function is mediated by inhibitory killer-cell immunoglobulin-like receptors (KIR) through the interaction with HLA class I molecules. Recently, HLA-C expression levels were shown to be correlated with protection against multiple outcomes of HIV-1 infection; ho...

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Main Authors: Körner, Christian, Granoff, Mitchell E., Amero, Molly A., Sirignano, Michael N., Vaidya, Sagar A., Jost, Stephanie, Allen, Todd M., Rosenberg, Eric S., Altfeld, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197106/
https://ncbi.nlm.nih.gov/pubmed/25043727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201444751
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