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CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation through the ZONAB pathway
Mutations in CFTR lead to dysfunction of tubular organs, which is currently attributed to impairment of its conductive properties. We now show that CFTR regulates tight junction assembly and epithelial cell differentiation through modulation of the ZO-1–ZONAB pathway. CFTR colocalizes with ZO-1 at t...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , , |
|---|---|
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
The Company of Biologists
2014
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197086/ https://ncbi.nlm.nih.gov/pubmed/25107366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.148098 |
| ট্যাগগুলো: |
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