S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo

BACKGROUND: Oxidative and nitrosative stress have been involved in gentamicin-induced nephrotoxicity. The purpose of this work was to study the effect of S-allylmercaptocysteine, a garlic derived compound, on gentamicin-induced oxidative and nitrosative stress and nephrotoxicity. In addition, the in...

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Pubblicato in:	BMC Clin Pharmacol
Autori principali:	Pedraza-Chaverrí, José, Barrera, Diana, Maldonado, Perla D, Chirino, Yolanda I, Macías-Ruvalcaba, Norma A, Medina-Campos, Omar N, Castro, Leticia, Salcedo, Marcos I, Hernández-Pando, Rogelio
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2004
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15119956/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6904-4-5
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