S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo

BACKGROUND: Oxidative and nitrosative stress have been involved in gentamicin-induced nephrotoxicity. The purpose of this work was to study the effect of S-allylmercaptocysteine, a garlic derived compound, on gentamicin-induced oxidative and nitrosative stress and nephrotoxicity. In addition, the in...

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Main Authors: Pedraza-Chaverrí, José, Barrera, Diana, Maldonado, Perla D, Chirino, Yolanda I, Macías-Ruvalcaba, Norma A, Medina-Campos, Omar N, Castro, Leticia, Salcedo, Marcos I, Hernández-Pando, Rogelio
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2004
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC419708/
https://ncbi.nlm.nih.gov/pubmed/15119956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-4-5
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