Cell state-specific metabolic dependency in hematopoiesis and leukemogenesis

The balance between oxidative and non-oxidative glucose metabolism is essential for a number of pathophysiological processes. By deleting enzymes that affect aerobic glycolysis with different potencies, we examine how modulating glucose metabolism specifically affects hematopoietic and leukemic cell...

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Autores principales: Wang, Ying-Hua, Israelsen, William J., Lee, Dongjun, Yu, Vionnie W.C., Jeanson, Nathaniel T., Clish, Clary B, Cantley, Lewis C., Heiden, Matthew G. Vander, Scadden, David T.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197056/
https://ncbi.nlm.nih.gov/pubmed/25215489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.07.048
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