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Copy Number Loss of the Interferon Gene Cluster in Melanomas Is Linked to Reduced T Cell Infiltrate and Poor Patient Prognosis

While immunotherapies are rapidly becoming mainstays of cancer treatment, significant gaps remain in our understanding of how to optimally target them, alone or in combination. Here we describe a novel method to monitor levels of immune cells and pathways in expression data from solid tumors using p...

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Bibliografische gegevens
Hoofdauteurs: Linsley, Peter S., Speake, Cate, Whalen, Elizabeth, Chaussabel, Damien
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196925/
https://ncbi.nlm.nih.gov/pubmed/25314013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109760
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