Group VIB Calcium-Independent Phospholipase A(2) (iPLA(2)γ) Regulates Platelet Activation, Hemostasis and Thrombosis in Mice

In platelets, group IVA cytosolic phospholipase A(2) (cPLA(2)α) has been implicated as a key regulator in the hydrolysis of platelet membrane phospholipids, leading to pro-thrombotic thromboxane A(2) and anti-thrombotic 12-(S)-hydroxyeicosatetranoic acid production. However, studies using cPLA(2)α-d...

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Main Authors: Yoda, Emiko, Rai, Kohmi, Ogawa, Mai, Takakura, Yuki, Kuwata, Hiroshi, Suzuki, Hidenori, Nakatani, Yoshihito, Murakami, Makoto, Hara, Shuntaro
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196902/
https://ncbi.nlm.nih.gov/pubmed/25313821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109409
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