Enhanced Cytotoxicity of Natural Killer Cells following the Acquisition of Chimeric Antigen Receptors through Trogocytosis

Natural killer (NK) cells have the capacity to target tumors and are ideal candidates for immunotherapy. Viral vectors have been used to genetically modify in vitro expanded NK cells to express chimeric antigen receptors (CARs), which confer cytotoxicity against tumors. However, use of viral transdu...

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Detalhes bibliográficos
Main Authors: Cho, Fu-Nan, Chang, Tsung-Hsien, Shu, Chih-Wen, Ko, Ming-Chin, Liao, Shuen-Kuei, Wu, Kang-Hsi, Yu, Ming-Sun, Lin, Shyh-Jer, Hong, Ying-Chung, Chen, Chien-Hsun, Hung, Chien-Hui, Chang, Yu-Hsiang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196898/
https://ncbi.nlm.nih.gov/pubmed/25313995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109352
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