Loss of γ-cytoplasmic actin triggers myofibroblast transition of human epithelial cells

Transdifferentiation of epithelial cells into mesenchymal cells and myofibroblasts plays an important role in tumor progression and tissue fibrosis. Such epithelial plasticity is accompanied by dramatic reorganizations of the actin cytoskeleton, although mechanisms underlying cytoskeletal effects on...

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Hauptverfasser: Lechuga, Susana, Baranwal, Somesh, Li, Chao, Naydenov, Nayden G., Kuemmerle, John F., Dugina, Vera, Chaponnier, Christine, Ivanov, Andrei I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2014
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196865/
https://ncbi.nlm.nih.gov/pubmed/25143399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-03-0815
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