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Loss of γ-cytoplasmic actin triggers myofibroblast transition of human epithelial cells
Transdifferentiation of epithelial cells into mesenchymal cells and myofibroblasts plays an important role in tumor progression and tissue fibrosis. Such epithelial plasticity is accompanied by dramatic reorganizations of the actin cytoskeleton, although mechanisms underlying cytoskeletal effects on...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4196865/ https://ncbi.nlm.nih.gov/pubmed/25143399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-03-0815 |
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