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Haploinsufficiency of kelch-like protein homolog 10 causes infertility in male mice

We identified a testis-specific gene encoding a protein containing a BTB/POZ domain and six kelch repeats, which we named kelch homolog 10 (KLHL10). KLHL10 displays high evolutionary conservation in mammals, as evidenced by 98.7% amino acid identity between mouse and human KLHL10. KLHL10 is exclusiv...

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Detalhes bibliográficos
Main Authors: Yan, Wei, Ma, Lang, Burns, Kathleen H., Matzuk, Martin M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC419685/
https://ncbi.nlm.nih.gov/pubmed/15136734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308025101
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